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Traditional Chinese Medicine ZHENG Identification Provides a Novel Stratification Approach in Patients with Allergic Rhinitis

机译:中医郑鉴为过敏性鼻炎患者提供了一种新的分层方法

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摘要

Background. We aimed to apply the ZHENG identification to provide an easy and useful tool to stratify the patients with allergic rhinitis (AR) through exploring the correlation between the quantified scores of AR symptoms and the TCM ZHENGs. Methods. A total of 114 AR patients were enrolled in this observational study. All participants received the examinations of anterior rhinoscopy and acoustic rhinometry. Their blood samples were collected for measurement of total serum immunoglobulin E (IgE), blood eosinophil count (Eos), and serum eosinophil cationic protein (ECP). They also received two questionnaire to assess the severity scores of AR symptoms and quantified TCM ZHENG scores. Multiple linear regression analysis was used to determine explanatory factors for the score of AR manifestations. Results. IgE and ECP level, duration of AR, the 2 derived TCMZHENG scores of “Yin-Xu − Yang-Xu”, and “Qi-Xu + Blood-Xu” were 5 explanatory variables to predict the severity scores of AR symptoms. The patients who had higher scores of “Yin-Xu − Yang-Xu” or “Qi-Xu + Blood-Xu” tended to manifest as “sneezer and runner” or “blockers,” respectively. Conclusions. The TCM ZHENG scores correlated with the severity scores of AR symptoms and provided an easy and useful tool to stratify the AR patients.
机译:背景。我们的目的是通过探索AR症状的量化评分与中医ZHENGs之间的相关性,应用ZHENG鉴定为分级过敏性鼻炎(AR)提供一个简单而有用的工具。方法。共有114名AR患者参加了这项观察性研究。所有参与者都接受了前鼻镜检查和声学鼻镜检查。收集他们的血液样本以测量血清总免疫球蛋白E(IgE),血嗜酸性粒细胞计数(Eos)和血清嗜酸性粒细胞阳离子蛋白(ECP)。他们还收到了两个问卷,以评估AR症状的严重程度评分和量化的中医ZHENG评分。多元线性回归分析用于确定AR表现得分的解释因素。结果。 IgE和ECP水平,AR的持续时间,“阴虚-阳虚”的2个TCMZHENG得分以及“气虚+血虚”的2个衍生变量是预测AR症状严重程度得分的5个解释变量。得分较高的患者,如“阴虚-阳虚”或“气虚+血虚”分别表现为“打喷嚏和跑步者”或“阻滞剂”。结论。中医症候评分与AR症状的严重程度评分相关,为将AR患者分层提供了一种简单而有用的工具。

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